Differences Between Familial and Sporadic Celiac Disease
نویسندگان
چکیده
منابع مشابه
Molecular and Survival Differences between Familial and Sporadic Gastric Cancers
Mismatch repair (MMR) and germline E-cadherin (CDH1) mutations are two of the major pathways of carcinogenesis in familial gastric cancer (GC). A total of 260 sporadic and 66 familial GC patients were enrolled and molecular and survival differences were compared. Familial GC patients had earlier onset and were diagnosed at an earlier stage and had both a better 5-year overall survival rate and ...
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DNA instability, reflected in altered patterns of short tandem repeat sequences (microsatellites) in dividing cells, has been described in hereditary non-polyposis colon cancer (HNPCC) and in other tumor types. Ovarian cancer (OC), although most often a sporadic cancer, can recur, with HNPCC, as part of the Lynch cancer family syndrome. In an investigation of microsatellite instability (MIN) in...
متن کاملDifferences between pediatric and adult celiac disease.
INTRODUCTION Celiac disease (CD) is a common autoimmune condition (involves 1-2% of the general population) that develops at any age in life but manifests differently in children and adults. OBJECTIVES To analyze clinical differences in disease expression between both groups, as well as findings at the time of diagnosis. METHODS A retrospective study of a series of patients diagnosed with C...
متن کاملFamilial prevalence of celiac disease.
BACKGROUND AND OBJECTIVE Serological screening enables us to detect patients of celiac disease (CD) before they develop serious complications. This study was planned to assess the prevalence of CD in the family members of index cases by serological screening. PATIENTS AND METHODS A prospective study was conducted on 50 children diagnosed to be having CD. Serological screening of the family me...
متن کاملThe Spectrum of Differences between Childhood and Adulthood Celiac Disease.
An old saying states that ''children are not little adults" and this certainly holds true for celiac disease, as there are many peculiar aspects regarding its epidemiology, diagnosis, clinical presentations, associated diseases, and response to treatment in pediatric compared to adult populations, to such an extent that it merits a description of its own. In fact, contrary to the past when it w...
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ژورنال
عنوان ژورنال: Digestive Diseases and Sciences
سال: 2020
ISSN: 0163-2116,1573-2568
DOI: 10.1007/s10620-020-06490-1